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Cues from plants to improve lipid content 2

Oil content of rape seed is being increased by increasing concentration of a yeast glycerol-3-phosphate dehydrogenase, which is involved with assembly of Triacyl Glycerols (TAG) by transgenesis .
This is further supported by several other studies in which overexpression of TAG assembly genes that increased seed oil content. For example, overexpression of glycerol-3-phosphate acyltransferase, lysophosphatidic acid acyltransferase, or diacylglycerol acyltransferase (DAGAT) all result in significant increases in plant lipid production .Hence, an attempt has also been made to use directed evolution to increase the efficiency of these enzymes.
Many of the genes involved in lipid metabolism in terrestrial plants have homologs in the sequenced microalgal genomes. Therefore, it is probable that at least some of the transgenic strategies that have been used to modify the lipid content in higher plants will also be effective with microalgae.
Wed August 04 2010 05:51:59 AM by Aayush 1716 views

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